Start here — in plain words
The strongest one is ranked #1 under Binding energy. Lower number = sticks stronger. Right now that is flufenoxuron. It is a candidate to test — not a proven killer.
Tap the blue button, bottom right. Ask normal questions like “Is it safe for bees?” It answers only from Affinix backend data — if it does not know, it says so.
Pick a chemical in Lab protocol below. That is the 7-step test plan a lab runs for you. Their result goes back into the backend and the ranking learns.
One liquid. Two jobs.
One bottle for the Oriental fruit fly (Bactrocera dorsalis). It should kill the flies that are here now, and stop the next ones from growing up. Same liquid underneath — for the farm, for the home, and for trash, where flies breed.
We checked before blending two. No single proven molecule does both for this fly. Our slow molecules — the benzoylureas, like flufenoxuron — only stop young flies from growing. They do not kill adult flies fast. So one molecule is not enough. The plan is a blend of two, in one liquid.
Lead blend to test — one bottle, two molecules inside
Hits chitin — the stuff a young fly needs to make its skin. The young fly cannot grow up. Docking score −10.694 against BdCHS2. This is the long-term job: no next wave of flies.
Hits the fly's nerves — the nAChR alpha 6 target (M4H3L1). In lab data: LC50 at 5 hours = 9.03 ppm, and LT50 under 2 hours at 100 ppm. This is the job people can see: flies here now die in hours, not days.
If spinosad does not work in the blend, the backup keeps novaluron for the slow job and swaps in indoxacarb for the fast job. Same test plan below, same four groups.
Farm
The problem: A female fly lays eggs inside fruit. The fruit rots from inside and cannot be sold. One bad shipment can also be turned away.
How the liquid helps: Put out early, in bait stations in the orchard. Adults die fast, so they stop laying eggs. Young flies do not grow up, so the flies do not come back week after week.
What matters most here: It must keep working for weeks, and bees must be protected — bait stations, not open spraying while bees are feeding.
Home
The problem: Flies around bananas, the kitchen, and the bin. You see a fly now, and you want it gone now — not next week.
How the liquid helps: A small bait liquid in the kitchen. The fast part kills the flies you can see. The slow part stops eggs already laid from turning into a new wave.
What matters most here: It has to feel like it works on day one, and it must be kept away from food, kids, and pets, in a closed bait station.
Trash
The problem: Bins and waste areas are where flies breed. Kill only the adults you see, and more hatch tomorrow.
How the liquid helps: Bait liquid in and around the bin area. Adults feeding there die fast. Young flies in the waste do not grow up, so the bin stops making new flies.
What matters most here: It has to be cheap, simple, and topped up easily — this is the everyday, repeat use.
Dual-action lab test plan
One test, four groups. This is how a lab finds out if the blend really does both jobs — or if one part is doing all the work. Same flies, same doses, same days for every group. Count dead adults in the first hours and days, then count how many young flies grow up over the full test.
Should stop young flies from growing up, but should not kill adults fast. If adults die fast here, something is wrong with the test.
Should kill adults in hours. Watch whether flies come back later — with no slow part, the next wave should still grow up.
The one that must do both: adults dead fast, and no next wave after. This group has to beat groups 1 and 2 together, not just one of them.
Plain liquid, nothing in it. This is the honest baseline. Every other group is judged against this one — no control, no proof.
Run bees alongside, in parallel. Same doses, on honeybees, at the same time. If the blend kills bees too, that must be known before anyone sells it — not after. Next step: send this four-group plan to a lab with the blend. Until that test runs, this folder is a plan to test — not a proven product.
Binding energy
Live from /dockTop candidates
Ranked by docking into real BdCHS2
2. Bistrifluron — −10.881
3. Fluazuron — −10.842
Top 10 — full ranking
Live from /rank| # | Molecule | Docking | Status |
|---|---|---|---|
| 1 | Flufenoxuron | −11.093 | CANDIDATE |
| 2 | Bistrifluron | −10.881 | CANDIDATE |
| 3 | Fluazuron | −10.842 | CANDIDATE |
Screening frequency
Last 28 daysTest these first — most to learn
Live from /learnTop binding pockets
Bee safety & lab protocol
Lab protocol — live insect test
- 30 flies per group, 5 doses, plus control
- Count dead every 24 hours for 7 days
- Pass if mortality is 50% higher than control and dose response is clear
- Run the same doses on honeybees in parallel
- Post the result to /results so the ranking learns
Lab results
Live from /resultsSafety ranges
FAIL
FAIL
FAIL